A Mild New Method for the C-Acylation of Ketone Enolates. A Convenient Synthesis of β-Keto Esters, -Thionoesters and Thioesters
| Data(s) |
2013
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| Resumo |
Abstract image.<br/><br/>A new method for ketone enolate C-acylation is described which utilizes alkyl pentafluorophenylcarbonates, thiocarbonates and thionocarbonates as the reactive acylating agents, and MgBr2.Et2O, DMAP and i-Pr2NEt as the reagents for enolization. A wide range of ketones have been observed to undergo clean C-acylation via this protocol. |
| Identificador | |
| Idioma(s) |
eng |
| Direitos |
info:eu-repo/semantics/closedAccess |
| Fonte |
Hale , K J , Grabski , M & Flasz , J T 2013 , ' A Mild New Method for the C-Acylation of Ketone Enolates. A Convenient Synthesis of β-Keto Esters, -Thionoesters and Thioesters ' Organic Letters , vol 15 , no. 2 , pp. 370-373 . DOI: 10.1021/ol303324a |
| Tipo |
article |
