Pepsin in bronchoalveolar lavage fluid:a specific and sensitive method of diagnosing gastro-oesophageal reflux-related pulmonary aspiration

Autoria(s): Farrell, S.; McMaster, Brian; Gibson, David; Shields, Michael; McCallion, W.A.
Data(s)

01/02/2006
Resumo

Gastro-oesophageal reflux (GOR)-related aspiration is associated with respiratory disease, but the current "gold standard" investigation, the lipid-laden macrophage index (LLMI), is flawed. A specific marker of GOR-related aspiration should originate in the stomach, but not the lung. An assay to detect gastric pepsin in the bronchoalveolar lavage (BAL) of children was developed and validated.
Identificador

http://pure.qub.ac.uk/portal/en/publications/pepsin-in-bronchoalveolar-lavage-fluid(c2126d4d-ab9a-4a54-8491-6c6a48814c0a).html

http://dx.doi.org/10.1016/j.jpedsurg.2005.11.002
Idioma(s)

eng
Direitos

info:eu-repo/semantics/restrictedAccess
Fonte

Farrell , S , McMaster , B , Gibson , D , Shields , M & McCallion , W A 2006 , ' Pepsin in bronchoalveolar lavage fluid : a specific and sensitive method of diagnosing gastro-oesophageal reflux-related pulmonary aspiration ' Journal of Pediatric Surgery , vol 41 , no. 2 , pp. 289-293 . DOI: 10.1016/j.jpedsurg.2005.11.002
Palavras-Chave #/dk/atira/pure/subjectarea/asjc/2700/2746 #Surgery
Tipo

article
Acesso ao item digital