Chromosome 2q31. 1 associates with ESRD in women with type 1 diabetes
| Data(s) |
01/10/2013
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| Resumo |
Sex and genetic variation influence the risk of developing diabetic nephropathy and ESRD in patients with type 1 diabetes. We performed a genome-wide association study in a cohort of 3652 patients from the Finnish Diabetic Nephropathy (FinnDiane) Study with type 1 diabetes to determine whether sex-specific genetic risk factors for ESRD exist. A common variant, rs4972593 on chromosome 2q31. 1, was associated with ESRD in women (P |
| Identificador |
http://dx.doi.org/10.1681/ASN.2012111122 http://www.scopus.com/inward/record.url?eid=2-s2.0-84885033741&partnerID=8YFLogxK |
| Idioma(s) |
eng |
| Direitos |
info:eu-repo/semantics/restrictedAccess |
| Fonte |
Sandholm , N , McKnight , A J , Salem , R M , Brennan , E P , Forsblom , C , Harjutsalo , V , Mäkinen , V-P , McKay , G J , Sadlier , D M , Williams , W W , Martin , F , Panduru , N M , Tarnow , L , Tuomilehto , J , Tryggvason , K , Zerbini , G , Comeau , M E , Langefeld , C D , Godson , C , Hirschhorn , J N , Maxwell , A P , Florez , J C & Groop , P-H 2013 , ' Chromosome 2q31. 1 associates with ESRD in women with type 1 diabetes ' Journal of the American Society of Nephrology , vol 24 , no. 10 , pp. 1537-1543 . DOI: 10.1681/ASN.2012111122 |
| Tipo |
article |
