pH-Sensitive brush polymer-drug conjugates by ring-opening metathesis copolymerization

Autoria(s): Zou, Jiong; Jafr, Goran; Themistou, Efrosyni; Yap, Yoonsing; Wintrob, Zachary A. P.; Alexandridis, Paschalis; Ceacareanu, Alice C.; Cheng, Chong
Data(s)

2011
Resumo

Representing a new category of polymer-drug conjugates, brush polymer-drug conjugates were prepared by ring-opening metathesis copolymerization. Following judicious structural design, these conjugates exhibited well-shielded drug moieties, significant water solubility, well-defined nanostructures, and acid-triggered drug release.
Identificador

http://pure.qub.ac.uk/portal/en/publications/phsensitive-brush-polymerdrug-conjugates-by-ringopening-metathesis-copolymerization(bc71d79d-ad0e-4f6b-97ee-0ebb74a147dc).html

http://dx.doi.org/10.1039/C0CC05531J
Idioma(s)

eng
Direitos

info:eu-repo/semantics/restrictedAccess
Fonte

Zou , J , Jafr , G , Themistou , E , Yap , Y , Wintrob , Z A P , Alexandridis , P , Ceacareanu , A C & Cheng , C 2011 , ' pH-Sensitive brush polymer-drug conjugates by ring-opening metathesis copolymerization ' Chemical Communications , vol 47 , no. 15 , pp. 4493-4495 . DOI: 10.1039/C0CC05531J
Tipo

article
Acesso ao item digital