Growth of human B cell colonies from peripheral blood of patients with systemic lupus erythematosus


Autoria(s): Fay, A C; Price, S; Trudgett, A; McCrea, J D; Haire, M; Boyd, M W; McNeill, T A
Data(s)

01/02/1986

Resumo

Human B cell colonies were grown from peripheral blood of 12 patients with systemic lupus erythematosus (SLE) and from 12 healthy control subjects. The SLE group showed a large increase (p less than 0.001) in the number of colony forming cells (CFC) present in peripheral blood as compared with controls. The CFC were of the pre-B cell type. There was also a loss of OKT8+ cell inhibition of B cell colony growth in the SLE group compared with control subjects.

Identificador

http://pure.qub.ac.uk/portal/en/publications/growth-of-human-b-cell-colonies-from-peripheral-blood-of-patients-with-systemic-lupus-erythematosus(cda4883c-224c-4d86-a67e-cc6ec2faf166).html

Idioma(s)

eng

Direitos

info:eu-repo/semantics/restrictedAccess

Fonte

Fay , A C , Price , S , Trudgett , A , McCrea , J D , Haire , M , Boyd , M W & McNeill , T A 1986 , ' Growth of human B cell colonies from peripheral blood of patients with systemic lupus erythematosus ' Annals of the Rheumatic Diseases , vol 45 , no. 2 , pp. 95-100 .

Palavras-Chave #Adult #Aged #B-Lymphocytes #Cells, Cultured #Female #Fluorescent Antibody Technique #Humans #Lupus Erythematosus, Systemic #Middle Aged #Stem Cells #T-Lymphocytes
Tipo

article