An experimental study of quinine blindness


Autoria(s): Buchanan, T. A.; Lyness, R. W.; Collins, A. D.; Gardiner, T. A.; Archer, D. B.
Data(s)

1987

Resumo

An experimental model of quinine induced blindness is presented. Electrophysiological, angiographical and morphological examinations were made. The occurrence of blindness and any recovery from blindness was dependent upon the dose of quinine taken. As no evidence of acute retinal ischaemia was found it is concluded that quinine is retinotoxic.

Identificador

http://pure.qub.ac.uk/portal/en/publications/an-experimental-study-of-quinine-blindness(f985d0a2-2661-47c6-8bef-df2fb95e8cb0).html

Idioma(s)

und

Direitos

info:eu-repo/semantics/restrictedAccess

Fonte

Buchanan , T A , Lyness , R W , Collins , A D , Gardiner , T A & Archer , D B 1987 , ' An experimental study of quinine blindness ' Eye , vol 1 ( Pt 4) , no. Pt 4 , pp. 522-524 .

Palavras-Chave #Animals #Blindness/chemically induced/physiopathology #Cats #Disease Models, Animal #Dose-Response Relationship, Drug #Electroretinography #Evoked Potentials, Visual #Female #Male #Microscopy, Electron #Quinine/toxicity #Retina/drug effects/ultrastructure #Retinal Diseases/pathology
Tipo

article