Induction of alloxan/streptozotocin diabetes in dogs: a revised experimental technique
Data(s) |
01/07/1993
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Resumo |
The diabetic dog represents an excellent model for use in many aspects of diabetic research. The present paper describes, in detail, a reproducible experimental protocol for the successful induction of chemical diabetes in beagles using a combination of the 2 pancreatic beta-cell cytoxic agents alloxan and streptozotocin. |
Identificador | |
Idioma(s) |
eng |
Direitos |
info:eu-repo/semantics/restrictedAccess |
Fonte |
Anderson , H , Stitt , A W , Gardiner , T A , Lloyd , S J & Archer , D B 1993 , ' Induction of alloxan/streptozotocin diabetes in dogs: a revised experimental technique ' Laboratory animals , vol 27 , no. 3 , pp. 281-285 . |
Palavras-Chave | #Alloxan #Animals #Blood Glucose/drug effects/metabolism #Diabetes Mellitus, Experimental/blood/chemically induced #Disease Models, Animal #Dogs #Glucose/administration & dosage #Reproducibility of Results #Streptozocin #Thymol/administration & dosage |
Tipo |
article |