First results on cell irradiation with laser-driven protons on the TARANIS system
| Data(s) |
2013
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| Resumo |
The ultra short duration of laser-driven multi-MeV ion bursts offers the possibility of radiobiological studies at extremely high dose rates. Employing the TARANIS Terawatt laser at Queen's University, the effect of proton irradiation at MeV-range energies on live cells has been investigated at dose rates exceeding 10 Gy/s as a single exposure. A clonogenic assay showed consistent lethal effects on V-79 live, cells, which, even at these dose rates, appear to be in line with previously published results employing conventional sources. A Relative Biological Effectiveness (RBE) of 1.4±0.2 at 10% survival is estimated from a comparison with a 225 kVp X-ray source. |
| Formato |
application/pdf |
| Identificador | |
| Idioma(s) |
eng |
| Direitos |
info:eu-repo/semantics/openAccess |
| Fonte |
Kar , S , Doria , D , Kakolee , K F , Prasad , R , Litt , S , Ahmed , H , Nersisyan , G , Lewis , C , Zepf , M , Borghesi , M , Schettino , G , Prise , K M , Fiorini , F , Kirby , D , Green , S , Jeynes , J C G , Merchant , M J & Kirkby , K J 2013 , First results on cell irradiation with laser-driven protons on the TARANIS system . in AIP Conference Proceedings . vol. 1546 , pp. 87-89 , AIP Conference 2012 , Catania , Italy , 18-19 October . DOI: 10.1063/1.4816612 |
| Tipo |
contributionToPeriodical |
