Risk factors related to inflammation and endothelial dysfunction in the DCCT/EDIC cohort and their relationship with nephropathy and macrovascular complications


Autoria(s): Lopes-Virella, Maria F; Carter, Rickey E; Gilbert, Gregory E; Klein, Richard L; Jaffa, Miran; Jenkins, Alicia J; Lyons, Timothy J; Garvey, W Timothy; Virella, Gabriel; Diabetes Control and Complications Trial/Epidemiology of Diabetes Intervention and Complications Cohort Study Group
Data(s)

01/10/2008

Resumo

Because endothelial cell dysfunction and inflammation are key contributors to the development of complications in type 1 diabetes, we studied risk factors related to endothelial dysfunction and inflammation (C-reactive protein and fibrinogen, soluble vascular cell adhesion molecule-1, intracellular adhesion molecule-1, and E-selectin, and fibrinolytic markers) in a subgroup of patients from the Diabetes Control and Complications Trial (DCCT)/Epidemiology of Diabetes Intervention and Complications (EDIC) study cohort.

Identificador

http://pure.qub.ac.uk/portal/en/publications/risk-factors-related-to-inflammation-and-endothelial-dysfunction-in-the-dcctedic-cohort-and-their-relationship-with-nephropathy-and-macrovascular-complications(29ab7a16-636a-4f14-b145-f0d82e92d357).html

http://dx.doi.org/10.2337/dc08-0659

Idioma(s)

eng

Direitos

info:eu-repo/semantics/restrictedAccess

Fonte

Lopes-Virella , M F , Carter , R E , Gilbert , G E , Klein , R L , Jaffa , M , Jenkins , A J , Lyons , T J , Garvey , W T , Virella , G & Diabetes Control and Complications Trial/Epidemiology of Diabetes Intervention and Complications Cohort Study Group 2008 , ' Risk factors related to inflammation and endothelial dysfunction in the DCCT/EDIC cohort and their relationship with nephropathy and macrovascular complications ' Diabetes Care , vol 31 , no. 10 , pp. 2006-12 . DOI: 10.2337/dc08-0659

Palavras-Chave #Adult #Albuminuria #Biological Markers #C-Reactive Protein #Carotid Arteries #Cohort Studies #Diabetes Mellitus, Type 1 #Diabetic Angiopathies #Diabetic Nephropathies #Endothelium, Vascular #Female #Humans #Inflammation #Male #Middle Aged #Models, Statistical #Regression Analysis #Risk Factors #Tunica Intima #Tunica Media
Tipo

article