Apoptosis induction by oxidized glycated LDL in human retinal capillary pericytes is independent of activation of MAPK signaling pathways
| Data(s) |
2009
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| Resumo |
Pericyte loss is a cardinal feature of early diabetic retinopathy. We previously reported that highly oxidized-glycated low density lipoprotein (HOG-LDL) induces pericyte apoptosis in vitro. In this study, we investigated the role of the mitogen-activated protein kinase (MAPK) signaling pathways in HOG-LDL-induced apoptosis in human pericytes. |
| Identificador | |
| Idioma(s) |
eng |
| Direitos |
info:eu-repo/semantics/restrictedAccess |
| Fonte |
Diffley , J M , Wu , M , Sohn , M , Song , W , Hammad , S M & Lyons , T J 2009 , ' Apoptosis induction by oxidized glycated LDL in human retinal capillary pericytes is independent of activation of MAPK signaling pathways ' Molecular Vision , vol 15 , pp. 135-45 . |
| Palavras-Chave | #Anthracenes #Apoptosis #Butadienes #Capillaries #Extracellular Signal-Regulated MAP Kinases #Humans #Imidazoles #JNK Mitogen-Activated Protein Kinases #Lipoproteins, LDL #MAP Kinase Signaling System #Nitriles #Pericytes #Phosphorylation #Protein Kinase Inhibitors #Pyridines #Retinal Vessels #Time Factors #p38 Mitogen-Activated Protein Kinases |
| Tipo |
article |
