LDL-containing immune complexes in the DCCT/EDIC cohort:associations with lipoprotein subclasses

Autoria(s): Klein, Richard L; Carter, Rickey E; Jenkins, Alicia J; Lyons, Timothy J; Baker, Nathaniel L; Gilbert, Gregory E; Virella, Gabriel; Lopes-Virella, Maria F; DCCT/EDIC Research Group
Data(s)

2011
Resumo

Immune complexes containing modified LDL (LDL-IC) and NMR-determined Total LDL particle concentrations are significantly associated with intima-media thickness (IMT). We analyzed the associations between concentrations of NMR-determined lipoprotein subclasses and LDL-IC in the DCCT/EDIC cohort. LDL-IC concentrations in women and men of the DCCT/EDIC cohort did not differ significantly and were positively associated with Total LDL particle concentrations in men and women (r=0.34, r=0.32, respectively; P
Identificador

http://pure.qub.ac.uk/portal/en/publications/ldlcontaining-immune-complexes-in-the-dcctedic-cohort(bc7e9930-782d-4330-9683-7a18ba3b6005).html

http://dx.doi.org/10.1016/j.jdiacomp.2010.03.001
Idioma(s)

eng
Direitos

info:eu-repo/semantics/restrictedAccess
Fonte

Klein , R L , Carter , R E , Jenkins , A J , Lyons , T J , Baker , N L , Gilbert , G E , Virella , G , Lopes-Virella , M F & DCCT/EDIC Research Group 2011 , ' LDL-containing immune complexes in the DCCT/EDIC cohort : associations with lipoprotein subclasses ' Journal of Diabetes and its Complications , vol 25 , no. 2 , pp. 73-82 . DOI: 10.1016/j.jdiacomp.2010.03.001
Palavras-Chave #Adult #Antigen-Antibody Complex #Blood Chemical Analysis #Clinical Trials as Topic #Cohort Studies #Diabetes Complications #Diabetes Mellitus, Type 1 #Female #Humans #Lipoproteins, LDL #Male #Middle Aged #Nuclear Magnetic Resonance, Biomolecular #Osmolar Concentration #Particle Size #Sex Characteristics
Tipo

article
Acesso ao item digital