Clinical and therapeutic relevance of PIM1 kinase in gastric cancer


Autoria(s): Yan, Benedict; Yau, Ee Xuan; Samanta, Sanjay; Ong, Chee Wee; Yong, Kol Jia; Ng, Lai Kuan; Bhattacharya, Bhaskar; Lim, Kiat Hon; Soong, Richie; Yeoh, Khay Guan; Deng, Niantao; Tan, Patrick; Lam, Yulin; Salto-Tellez, Manuel; Singapore Gastric Cancer Consortium
Data(s)

01/04/2012

Resumo

Gastric cancer is a leading cause of cancer-related mortality, and chemotherapeutic options are currently limited. PIM1 kinase, an oncogene that promotes tumorigenesis in several cancer types, might represent a novel therapeutic target in gastric cancer.

Identificador

http://pure.qub.ac.uk/portal/en/publications/clinical-and-therapeutic-relevance-of-pim1-kinase-in-gastric-cancer(adbcc9ef-a100-4af2-ad4d-030007c7d729).html

http://dx.doi.org/10.1007/s10120-011-0097-2

Idioma(s)

eng

Direitos

info:eu-repo/semantics/restrictedAccess

Fonte

Yan , B , Yau , E X , Samanta , S , Ong , C W , Yong , K J , Ng , L K , Bhattacharya , B , Lim , K H , Soong , R , Yeoh , K G , Deng , N , Tan , P , Lam , Y , Salto-Tellez , M & Singapore Gastric Cancer Consortium 2012 , ' Clinical and therapeutic relevance of PIM1 kinase in gastric cancer ' GBER, Global Built Environment Review (issn: 1474-6824) , vol 15 , no. 2 , pp. 188-97 . DOI: 10.1007/s10120-011-0097-2

Palavras-Chave #Real-Time Polymerase Chain Reaction #Humans #In Situ Hybridization, Fluorescence #Aged #Cell Line, Tumor #Gene Expression Regulation, Neoplastic #Kaplan-Meier Estimate #Protein Array Analysis #Proto-Oncogene Proteins c-pim-1 #Blotting, Western #Stomach Neoplasms #Middle Aged #Immunohistochemistry #Cell Transformation, Neoplastic #Female #Male #Survival Analysis
Tipo

article