JMJD6 is a driver of cellular proliferation and motility and a marker of poor prognosis in breast cancer
| Data(s) |
2012
|
|---|---|
| Resumo |
We developed an analytic strategy that correlates gene expression and clinical outcomes as a means to identify novel candidate oncogenes operative in breast cancer. This analysis, followed by functional characterization, resulted in the identification of Jumonji Domain Containing 6 (JMJD6) protein as a novel driver of oncogenic properties in breast cancer. |
| Identificador | |
| Idioma(s) |
eng |
| Direitos |
info:eu-repo/semantics/restrictedAccess |
| Fonte |
Lee , Y F , Miller , L D , Chan , X B , Black , M A , Pang , B , Ong , C W , Salto-Tellez , M , Liu , E T & Desai , K V 2012 , ' JMJD6 is a driver of cellular proliferation and motility and a marker of poor prognosis in breast cancer ' Breast Cancer Research , vol 14 , no. 3 , pp. R85 . DOI: 10.1186/bcr3200 |
| Palavras-Chave | #Cell Movement #Disease-Free Survival #Jumonji Domain-Containing Histone Demethylases #Humans #Prognosis #Breast Neoplasms #Cell Line, Tumor #RNA, Small Interfering #Cell Proliferation #Gene Expression Regulation, Neoplastic #Transforming Growth Factor beta2 #MCF-7 Cells #RNA Interference #Tumor Markers, Biological #Cyclin E #Female |
| Tipo |
article |
