The United Kingdom Glaucoma Treatment Study:a multicenter, randomized, placebo-controlled clinical trial: design and methodology
Data(s) |
01/01/2013
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Resumo |
Elevated intraocular pressure (IOP) is a major risk factor for the deterioration of open-angle glaucoma (OAG); medical IOP reduction is the standard treatment, yet no randomized placebo-controlled study of medical IOP reduction has been undertaken previously. The United Kingdom Glaucoma Treatment Study (UKGTS) tests the hypothesis that treatment with a topical prostaglandin analog, compared with placebo, reduces the frequency of visual field (VF) deterioration events in OAG patients by 50% over a 2-year period. |
Identificador | |
Idioma(s) |
eng |
Direitos |
info:eu-repo/semantics/restrictedAccess |
Fonte |
Garway-Heath , D F , Lascaratos , G , Bunce , C , Crabb , D P , Russell , R A , Shah , A , United Kingdom Glaucoma Treatment Study Investigators & Azuara-Blanco , A 2013 , ' The United Kingdom Glaucoma Treatment Study : a multicenter, randomized, placebo-controlled clinical trial: design and methodology ' Ophthalmology , vol 120 , no. 1 , pp. 68-76 . DOI: 10.1016/j.ophtha.2012.07.028 |
Palavras-Chave | #Intraocular Pressure #Vision Disorders #Blood Pressure #Double-Blind Method #Humans #Aged #Prostaglandins F, Synthetic #Antihypertensive Agents #Visual Fields #Research Design #Ophthalmoscopy #Great Britain #Quality Assurance, Health Care #Medication Adherence #Prospective Studies #Scanning Laser Polarimetry #Risk Factors #Glaucoma, Open-Angle #Treatment Outcome #Middle Aged #Tomography, Optical Coherence #Visual Acuity #/dk/atira/pure/subjectarea/asjc/2700/2731 #Ophthalmology |
Tipo |
article |