Serological correlate of protection against norovirus-induced gastroenteritis


Autoria(s): Reeck, Amanda; Kavanagh, Owen; Estes, Mary K; Opekun, Antone R; Gilger, Mark A; Graham, David Y; Atmar, Robert L
Data(s)

15/10/2010

Resumo

Norovirus infection is the leading cause of acute nonbacterial gastroenteritis. Histoblood group antigens (HBGAs) are host susceptibility determinants for Norwalk virus (NV) infection. We hypothesized that antibodies that block NV-HBGA binding are associated with protection from clinical illness following NV exposure.

Identificador

http://pure.qub.ac.uk/portal/en/publications/serological-correlate-of-protection-against-norovirusinduced-gastroenteritis(0ad45b8f-bff8-40e9-afdc-bc2b716cc491).html

http://dx.doi.org/10.1086/656364

Idioma(s)

eng

Direitos

info:eu-repo/semantics/restrictedAccess

Fonte

Reeck , A , Kavanagh , O , Estes , M K , Opekun , A R , Gilger , M A , Graham , D Y & Atmar , R L 2010 , ' Serological correlate of protection against norovirus-induced gastroenteritis ' The Journal of Infectious Diseases , vol 202 , no. 8 , pp. 1212-8 . DOI: 10.1086/656364

Palavras-Chave #Young Adult #Reproducibility of Results #Humans #Norwalk virus #Biological Assay #Polysaccharides #Virus Shedding #Antibodies, Blocking #Caliciviridae Infections #Adult #Middle Aged #Adolescent #Gastroenteritis
Tipo

article