Klebsiella pneumoniae OmpA confers resistance to antimicrobial peptides


Autoria(s): Llobet, Enrique; March, Catalina; Giménez, Paloma; Bengoechea, José A
Data(s)

2009

Resumo

A Klebsiella pneumoniae ompA mutant was more susceptible to antimicrobial peptides (APs) than the wild type. Susceptibility did not result from surface changes other than the absence of OmpA. Our data suggest that OmpA is implicated in the activation of yet-unknown systems dedicated to ameliorating AP cytotoxicity.

Identificador

http://pure.qub.ac.uk/portal/en/publications/klebsiella-pneumoniae-ompa-confers-resistance-to-antimicrobial-peptides(23dbdd60-226c-4f30-97b0-8694f0753470).html

http://dx.doi.org/10.1128/AAC.00657-08

Idioma(s)

eng

Direitos

info:eu-repo/semantics/restrictedAccess

Fonte

Llobet , E , March , C , Giménez , P & Bengoechea , J A 2009 , ' Klebsiella pneumoniae OmpA confers resistance to antimicrobial peptides ' Antimicrobial Agents and Chemotherapy , vol 53 , no. 1 , pp. 298-302 . DOI: 10.1128/AAC.00657-08

Tipo

article