Histone deacetylase 3 is critical in endothelial survival and atherosclerosis development in response to disturbed flow
| Data(s) |
2010
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|---|---|
| Resumo |
Histone deacetylase 3 (HDAC3) is known to play a crucial role in the differentiation of endothelial progenitors. The role of HDAC3 in mature endothelial cells, however, is not well understood. Here, we investigated the function of HDAC3 in preserving endothelial integrity in areas of disturbed blood flow, ie, bifurcation areas prone to atherosclerosis development. |
| Identificador | |
| Idioma(s) |
eng |
| Direitos |
info:eu-repo/semantics/restrictedAccess |
| Fonte |
Zampetaki , A , Zeng , L , Margariti , A , Xiao , Q , Li , H , Zhang , Z , Pepe , A E , Wang , G , Habi , O , deFalco , E , Cockerill , G , Mason , J C , Hu , Y & Xu , Q 2010 , ' Histone deacetylase 3 is critical in endothelial survival and atherosclerosis development in response to disturbed flow ' Circulation , vol 121 , no. 1 , pp. 132-42 . DOI: 10.1161/CIRCULATIONAHA.109.890491 |
| Tipo |
article |
