Innate host defense functions of secretory leucoprotease inhibitor
Data(s) |
01/12/2007
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Resumo |
Chronic lung diseases such as cystic fibrosis and emphysema are characterized by a protease burden, an infective process and a dominant proinflammatory profile. Secretory leucoprotease inhibitor (SLPI) is a prominent innate immune protein of the respiratory tract, possessing serine protease inhibitor activity, antibacterial activity, and anti-inflammatory/immunomodulatory activity. In the course of this review, the authors highlight the findings from a range of studies that illustrate the multiple functions of SLPI and its role in the resolution of the immune response. |
Identificador | |
Idioma(s) |
eng |
Direitos |
info:eu-repo/semantics/restrictedAccess |
Fonte |
Weldon , S & Taggart , C C 2007 , ' Innate host defense functions of secretory leucoprotease inhibitor ' Experimental Lung Research , vol 33 , no. 10 , pp. 485-91 . DOI: 10.1080/01902140701756547 |
Palavras-Chave | #/dk/atira/pure/subjectarea/asjc/2700/2740 #Pulmonary and Respiratory Medicine |
Tipo |
article |