Cathepsin F cysteine protease of the human liver fluke, Opisthorchis viverrini


Autoria(s): Pinlaor, Porntip; Kaewpitoon, Natthawut; Laha, Thewarach; Sripa, Banchob; Kaewkes, Sasithorn; Morales, Maria E; Mann, Victoria H; Parriott, Sandi K; Suttiprapa, Sutas; Robinson, Mark W; To, Joyce; Dalton, John P; Loukas, Alex; Brindley, Paul J
Data(s)

2009

Resumo

The liver fluke Opisthorchis viverrini is classified as a class I carcinogen due to the association between cholangiocarcinoma and chronic O. viverrini infection. During its feeding activity within the bile duct, the parasite secretes several cathepsin F cysteine proteases that may induce or contribute to the pathologies associated with hepatobiliary abnormalities.

Identificador

http://pure.qub.ac.uk/portal/en/publications/cathepsin-f-cysteine-protease-of-the-human-liver-fluke-opisthorchis-viverrini(9d353217-3298-4010-8594-3d92c7167e32).html

http://dx.doi.org/10.1371/journal.pntd.0000398

Idioma(s)

eng

Direitos

info:eu-repo/semantics/restrictedAccess

Fonte

Pinlaor , P , Kaewpitoon , N , Laha , T , Sripa , B , Kaewkes , S , Morales , M E , Mann , V H , Parriott , S K , Suttiprapa , S , Robinson , M W , To , J , Dalton , J P , Loukas , A & Brindley , P J 2009 , ' Cathepsin F cysteine protease of the human liver fluke, Opisthorchis viverrini ' PLoS neglected tropical diseases , vol 3 , no. 3 , e398 , pp. e398 . DOI: 10.1371/journal.pntd.0000398

Palavras-Chave #/dk/atira/pure/subjectarea/asjc/2700/2725 #Infectious Diseases #/dk/atira/pure/subjectarea/asjc/2700/2739 #Public Health, Environmental and Occupational Health #/dk/atira/pure/subjectarea/asjc/3000 #Pharmacology, Toxicology and Pharmaceutics(all)
Tipo

article