Discovery and SAR of a novel series of non-MPEP site mGlu(5) PAMs based on an aryl glycine sulfonammide scaffold


Autoria(s): Williams, Richard
Data(s)

2012

Resumo

Herein we report the discovery and SAR of a novel series of non-MPEP site metabotropic glutamate receptor 5 (mGlu(5)) positive allosteric modulators (PAMs) based on an aryl glycine sulfonamide scaffold. This series represents a rare non-MPEP site mGlu(5) PAM chemotype. <br/> <br/>

Identificador

http://pure.qub.ac.uk/portal/en/publications/discovery-and-sar-of-a-novel-series-of-nonmpep-site-mglu5-pams-based-on-an-aryl-glycine-sulfonammide-scaffold(cab33d9c-9420-47c9-a4a4-3833114f128c).html

Idioma(s)

eng

Direitos

info:eu-repo/semantics/restrictedAccess

Fonte

Williams , R 2012 , ' Discovery and SAR of a novel series of non-MPEP site mGlu(5) PAMs based on an aryl glycine sulfonammide scaffold ' Bioorganic & Medicinal Chemistry Letters .

Tipo

article