Diastereoselective 1,3-dipolar cycloaddition of pyrylium ylides with chiral enamides
| Data(s) |
2012
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|---|---|
| Resumo |
Chiral enamides5f-i were found to react with pyrylium ylides to give cycloadducts 6d-i in good yields with an excellent level of stereoselectivity. The chiral auxiliary was successfully removed on hydrogenolysis of compound 6f in continuous flow (H-Cube) resulting in the first asymmetric synthesis of complex amine 8. |
| Formato |
application/pdf |
| Identificador | |
| Idioma(s) |
eng |
| Direitos |
info:eu-repo/semantics/openAccess |
| Fonte |
Tchabanenko , K , Sloan , C , Bunetel , Y-M & Mullen , P 2012 , ' Diastereoselective 1,3-dipolar cycloaddition of pyrylium ylides with chiral enamides ' Organic and Biomolecular Chemistry , vol 10 , no. 21 , pp. 4215-4219 . DOI: 10.1039/c2ob07007c |
| Palavras-Chave | #/dk/atira/pure/subjectarea/asjc/1600/1606 #Physical and Theoretical Chemistry #/dk/atira/pure/subjectarea/asjc/1600/1605 #Organic Chemistry #/dk/atira/pure/subjectarea/asjc/1300/1303 #Biochemistry |
| Tipo |
article |
