Determining the minimum clinically important differences for outcomes in the DOMINO trial


Autoria(s): Howard, Robert; Phillips, Patrick; Johnson, Tony; O'Brien, John; Sheehan, Bart; Lindesay, James; Bentham, Peter; Burns, Alistair; Ballard, Clive; Holmes, Clive; McKeith, Ian; Barber, Robert; Dening, Tom; Ritchie, Craig; Jones, Rob; Baldwin, Ashley; Passmore, Peter; Findlay, David; Hughes, Alan; Macharouthu, Ajay; Banerjee, Sube; Jones, Roy; Knapp, Martin; Brown, Richard G; Jacoby, Robin; Adams, Jessica; Griffin, Mary; Gray, Richard
Data(s)

01/08/2011

Resumo

Although less likely to be reported in clinical trials than expressions of the statistical significance of differences in outcomes, whether or not a treatment has delivered a specified minimum clinically important difference (MCID) is also relevant to patients and their caregivers and doctors. Many dementia treatment randomised controlled trials (RCTs) have not reported MCIDs and, where they have been done, observed differences have not reached these.

Identificador

http://pure.qub.ac.uk/portal/en/publications/determining-the-minimum-clinically-important-differences-for-outcomes-in-the-domino-trial(0a647107-e432-426d-8ee3-f619e8214781).html

http://dx.doi.org/10.1002/gps.2607

Idioma(s)

eng

Direitos

info:eu-repo/semantics/restrictedAccess

Fonte

Howard , R , Phillips , P , Johnson , T , O'Brien , J , Sheehan , B , Lindesay , J , Bentham , P , Burns , A , Ballard , C , Holmes , C , McKeith , I , Barber , R , Dening , T , Ritchie , C , Jones , R , Baldwin , A , Passmore , P , Findlay , D , Hughes , A , Macharouthu , A , Banerjee , S , Jones , R , Knapp , M , Brown , R G , Jacoby , R , Adams , J , Griffin , M & Gray , R 2011 , ' Determining the minimum clinically important differences for outcomes in the DOMINO trial ' International Journal of Geriatric Psychiatry , vol 26 , no. 8 , pp. 812-7 . DOI: 10.1002/gps.2607

Palavras-Chave #/dk/atira/pure/subjectarea/asjc/2700/2717 #Geriatrics and Gerontology #/dk/atira/pure/subjectarea/asjc/2700/2738 #Psychiatry and Mental health
Tipo

article