Assessment of three Resistance-Nodulation-Cell Division drug efflux transporters of Burkholderia cenocepacia in intrinsic antibiotic resistance


Autoria(s): Buroni, Silvia; Pasca, Maria R; Flannagan, Ronald S; Bazzini, Silvia; Milano, Anna; Bertani, Iris; Venturi, Vittorio; Valvano, Miguel A; Riccardi, Giovanna
Data(s)

2009

Resumo

Burkholderia cenocepacia are opportunistic Gram-negative bacteria that can cause chronic pulmonary infections in patients with cystic fibrosis. These bacteria demonstrate a high-level of intrinsic antibiotic resistance to most clinically useful antibiotics complicating treatment. We previously identified 14 genes encoding putative Resistance-Nodulation-Cell Division (RND) efflux pumps in the genome of B. cenocepacia J2315, but the contribution of these pumps to the intrinsic drug resistance of this bacterium remains unclear.

Identificador

http://pure.qub.ac.uk/portal/en/publications/assessment-of-three-resistancenodulationcell-division-drug-efflux-transporters-of-burkholderia-cenocepacia-in-intrinsic-antibiotic-resistance(7a096925-1595-4d27-b17b-620da7fcc705).html

http://dx.doi.org/10.1186/1471-2180-9-200

Idioma(s)

eng

Direitos

info:eu-repo/semantics/restrictedAccess

Fonte

Buroni , S , Pasca , M R , Flannagan , R S , Bazzini , S , Milano , A , Bertani , I , Venturi , V , Valvano , M A & Riccardi , G 2009 , ' Assessment of three Resistance-Nodulation-Cell Division drug efflux transporters of Burkholderia cenocepacia in intrinsic antibiotic resistance ' BMC Microbiology , vol 9 , 200 , pp. 200 . DOI: 10.1186/1471-2180-9-200

Palavras-Chave #/dk/atira/pure/subjectarea/asjc/2400/2404 #Microbiology #/dk/atira/pure/subjectarea/asjc/2700/2726 #Microbiology (medical)
Tipo

article