High confidence prediction of essential genes in burkholderia cenocepacia


Autoria(s): Juhas, Mario; Stark, Manuel; von Mering, Christian; Lumjiaktase, Puthapoom; Crook, Derrick W; Valvano, Miguel A; Eberl, Leo
Data(s)

29/06/2012

Resumo

Essential genes are absolutely required for the survival of an organism. The identification of essential genes, besides being one of the most fundamental questions in biology, is also of interest for the emerging science of synthetic biology and for the development of novel antimicrobials. New antimicrobial therapies are desperately needed to treat multidrug-resistant pathogens, such as members of the Burkholderia cepacia complex.

Identificador

http://pure.qub.ac.uk/portal/en/publications/high-confidence-prediction-of-essential-genes-in-burkholderia-cenocepacia(ac0fbd50-1246-4966-8771-42f4e142ad48).html

http://dx.doi.org/10.1371/journal.pone.0040064

Idioma(s)

eng

Direitos

info:eu-repo/semantics/restrictedAccess

Fonte

Juhas , M , Stark , M , von Mering , C , Lumjiaktase , P , Crook , D W , Valvano , M A & Eberl , L 2012 , ' High confidence prediction of essential genes in burkholderia cenocepacia ' PLoS ONE , vol 7 , no. 6 , e40064 , pp. e40064 . DOI: 10.1371/journal.pone.0040064

Palavras-Chave #/dk/atira/pure/subjectarea/asjc/1100 #Agricultural and Biological Sciences(all) #/dk/atira/pure/subjectarea/asjc/1300 #Biochemistry, Genetics and Molecular Biology(all) #/dk/atira/pure/subjectarea/asjc/2700 #Medicine(all)
Tipo

article