Domino Alkene-Isomerization–Claisen Rearrangement Strategy to Substituted Allylsilanes

Autoria(s): Cook, Matthew; McLaughlin, Mark
Data(s)

17/02/2012
Resumo

A one-pot isomerization–Claisen protocol has been developed for the synthesis of highly substituted allylsilanes. Monosilylated divinyl ethers can be isomerized using a cationic iridium(I) catalyst followed by a thermal Claisen rearrangement to provide the allylsilanes in excellent yields and diastereoselectivities.
Identificador

http://pure.qub.ac.uk/portal/en/publications/domino-alkeneisomerizationclaisen-rearrangement-strategy-to-substituted-allylsilanes(faf9ec7a-6c17-486e-84c9-e47d1e5e38a4).html

http://dx.doi.org/10.1021/jo202560g
Idioma(s)

eng
Direitos

info:eu-repo/semantics/restrictedAccess
Fonte

Cook , M & McLaughlin , M 2012 , ' Domino Alkene-Isomerization–Claisen Rearrangement Strategy to Substituted Allylsilanes ' Journal of Organic Chemistry , vol 77 , no. 4 , pp. 2058-2063 . DOI: 10.1021/jo202560g
Palavras-Chave #/dk/atira/pure/subjectarea/asjc/1600/1605 #Organic Chemistry
Tipo

article
Acesso ao item digital