Oxidative stress and increased type-IV collagenase levels in bronchoalveolar lavage fluid from newborn babies


Autoria(s): Schock, B.C.; Sweet, D.G.; Ennis, Madeleine; Warner, J.A.; Young, Ian; Halliday, H.L.
Data(s)

2001

Resumo

Oxidative stress may increase lung permeability by upregulation of matrix-metalloproteinase-9 (MMP-8), a type-IV collagenase that can disrupt alveolar basement membranes. We have compared a marker of oxidative stress (protein carbonyl residues) with levels of MMP-8 and its inhibitor, tissue inhibitor of metalloproteinase-1 (TIMP-1), in bronchoalveolar lavage samples from newborn babies. Bronchoalveolar lavage samples (n = 87, two from each time point) were taken in the first 6 postnatal days from 41 ventilated babies: 18 of

Identificador

http://pure.qub.ac.uk/portal/en/publications/oxidative-stress-and-increased-typeiv-collagenase-levels-in-bronchoalveolar-lavage-fluid-from-newborn-babies(0e9d325c-f102-4cb8-83c0-346a7d9ff879).html

Idioma(s)

eng

Direitos

info:eu-repo/semantics/restrictedAccess

Fonte

Schock , B C , Sweet , D G , Ennis , M , Warner , J A , Young , I & Halliday , H L 2001 , ' Oxidative stress and increased type-IV collagenase levels in bronchoalveolar lavage fluid from newborn babies ' Pediatric Research , vol 50 , no. 1 I , pp. 29-33 .

Palavras-Chave #/dk/atira/pure/subjectarea/asjc/2700/2735 #Pediatrics, Perinatology, and Child Health
Tipo

article