Characterisation of a C1qtnf5 Ser163Arg Knock-In Mouse Model of Late-Onset Retinal Macular Degeneration
| Data(s) |
16/11/2011
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| Resumo |
A single founder mutation resulting in a Ser163Arg substitution in the C1QTNF5 gene product causes autosomal dominant late-onset retinal macular degeneration (L-ORMD) in humans, which has clinical and pathological features resembling age-related macular degeneration. We generated and characterised a mouse |
| Formato |
application/pdf |
| Identificador | |
| Idioma(s) |
eng |
| Direitos |
info:eu-repo/semantics/openAccess |
| Fonte |
Shu , X H , Luhmann , U F O , Aleman , T S , Barker , S E , Lennon , A , Tulloch , B , Chen , M , Xu , H , Jacobson , S G , Ali , A S & Wright , A 2011 , ' Characterisation of a C1qtnf5 Ser163Arg Knock-In Mouse Model of Late-Onset Retinal Macular Degeneration ' PLoS ONE , vol 6 , no. 11 , e27433 , pp. e27433 . DOI: 10.1371/journal.pone.0027433 |
| Palavras-Chave | #/dk/atira/pure/subjectarea/asjc/1100 #Agricultural and Biological Sciences(all) #/dk/atira/pure/subjectarea/asjc/1300 #Biochemistry, Genetics and Molecular Biology(all) #/dk/atira/pure/subjectarea/asjc/2700 #Medicine(all) |
| Tipo |
article |
