Enantioselective dioxygenase-catalysed formation and thermal racemisation of chiral thiophene sulfoxides
| Data(s) |
1996
|
|---|---|
| Resumo |
Substituted chiral thiophene 1-oxides and their cycloadducts of variable enantiopurity have been isolated as products of dioxygenase-catalysed sulfoxidation of the corresponding thiophenes using intact cells of Pseudomonas putida; thermal racemization (Delta G(double dagger) = 25.1 kcal mol(-1)) of the enantiopure metabolite (1R)-2-methylbenzo[b]thiophene 1-oxide has been observed. |
| Identificador | |
| Idioma(s) |
eng |
| Direitos |
info:eu-repo/semantics/restrictedAccess |
| Fonte |
Boyd , D , Sharma , N , Haughey , S A , Malone , J , McMurray , B T , Sheldrake , G , Allen , C & Dalton , H 1996 , ' Enantioselective dioxygenase-catalysed formation and thermal racemisation of chiral thiophene sulfoxides ' Chemical Communications , vol NA , pp. 2363-2364 . |
| Tipo |
article |
