DNA Reorientation on Au Nanoparticles: Label-Free Detection of Hybridization by Surface Enhanced Raman Spectroscopy
| Data(s) |
21/10/2011
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| Identificador | |
| Idioma(s) |
eng |
| Direitos |
info:eu-repo/semantics/restrictedAccess |
| Fonte |
Papadopoulou , E & Bell , S E J 2011 , ' DNA Reorientation on Au Nanoparticles: Label-Free Detection of Hybridization by Surface Enhanced Raman Spectroscopy ' Chemical Communications , vol 47 , no. 39 , pp. 10966-10968 . DOI: 10.1039/c1cc13705k |
| Palavras-Chave | #/dk/atira/pure/subjectarea/asjc/2500/2506 #Metals and Alloys #/dk/atira/pure/subjectarea/asjc/2500/2505 #Materials Chemistry #/dk/atira/pure/subjectarea/asjc/2500/2508 #Surfaces, Coatings and Films #/dk/atira/pure/subjectarea/asjc/2500/2504 #Electronic, Optical and Magnetic Materials #/dk/atira/pure/subjectarea/asjc/2500/2503 #Ceramics and Composites #/dk/atira/pure/subjectarea/asjc/1500/1503 #Catalysis #/dk/atira/pure/subjectarea/asjc/1600 #Chemistry(all) |
| Tipo |
article |
| Resumo |
<p>DNA sequences attached to Au nanoparticles via thiol linkers stand up from the surface, giving preferential enhancement of the adenine ring breathing SERS band. Non-specific binding via the nucleobases reorients the DNA, reducing this effect. This change in intensity on reorientation was utilised for label-free detection of hybridization of a molecular beacon.</p> |
