Network biology: a direct approach to study biological function


Autoria(s): Emmert-Streib, Frank; Glazko, G.V.
Data(s)

01/07/2011

Resumo

In this paper we discuss the dualism of gene networks and their role in systems biology. We argue that gene networks ( 1) can serve as a conceptual framework, forming a fundamental level of a phenomenological description, and ( 2) are a means to represent and analyze data. The latter point does not only allow a systems analysis but is even amenable for a direct approach to study biological function. Here we focus on the clarity of our main arguments and conceptual meaning of gene networks, rather than the causal inference of gene networks from data. (C) 2010 John Wiley & Sons, Inc. WIREs Syst Biol Med 2011 3 379-391 DOI: 10.1002/wsbm.134

Identificador

http://pure.qub.ac.uk/portal/en/publications/network-biology-a-direct-approach-to-study-biological-function(e4f07442-f45d-462e-b1c3-5d1bef5042e2).html

http://dx.doi.org/10.1002/wsbm.134

Idioma(s)

eng

Direitos

info:eu-repo/semantics/restrictedAccess

Fonte

Emmert-Streib , F & Glazko , G V 2011 , ' Network biology: a direct approach to study biological function ' WILEY INTERDISCIPLINARY REVIEWS-SYSTEMS BIOLOGY AND MEDICINE , vol 3 , no. 4 , pp. 379-391 . DOI: 10.1002/wsbm.134

Palavras-Chave #/dk/atira/pure/subjectarea/asjc/1300/1301 #Biochemistry, Genetics and Molecular Biology (miscellaneous) #/dk/atira/pure/subjectarea/asjc/2700/2701 #Medicine (miscellaneous)
Tipo

article