In Vitro and In Vivo Effects of Natural Putative Secretagogues of Glucagon-Like Peptide-1 (GLP-1)
| Data(s) |
2011
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| Resumo |
Glucagon-like peptide-1 (GLP-1) is an intestinal hormone with well-established glucose-lowering activity. The in vitro and in vivo actions of natural putative secretagogues of GLP-1 were investigated. The acute GLP-1 releasing activity of olive leaf extract (OLE), glutamine (GLN), alpha casein (ACAS), beta casein (BCAS) and chlorogenic acid (CGA) were assessed in STC-1 cells and C57BL/6 mice. All compounds except ACAS significantly increased acute in vitro GLP-1 secretion (66-386%; P |
| Identificador | |
| Idioma(s) |
eng |
| Direitos |
info:eu-repo/semantics/closedAccess |
| Fonte |
Rafferty , E P , Wylie , A R , Elliott , C T , Chevallier , O P , Grieve , D J & Green , B D 2011 , ' In Vitro and In Vivo Effects of Natural Putative Secretagogues of Glucagon-Like Peptide-1 (GLP-1) ' Scientia Pharmaceutica , vol 79 , no. 3 , pp. 615-621 . DOI: 10.3797/scipharm.1104-16 |
| Palavras-Chave | #/dk/atira/pure/subjectarea/asjc/3000/3003 #Pharmaceutical Science |
| Tipo |
article |
