Anthracene-modified oligonucleotides as fluorescent DNA mismatch sensors: discrimination between various base-pair mismatches
Data(s) |
01/03/2011
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Resumo |
A fluorescent anthracene-tagged DNA probe has been shown to respond to various DNA sequences by changes to its emission signal upon duplex formation. The fluorescence response for duplexes containing a single mismatch near the anthracene site has been found to be very sensitive to its composition, with the emission signal increasing for a CA mismatch and decreasing for CT and CC mismatches. |
Identificador | |
Idioma(s) |
eng |
Direitos |
info:eu-repo/semantics/restrictedAccess |
Fonte |
Duprey , J L H A , Bassani , D M , Hyde , E I , Ludwig , C , Rodger , A , Vyle , J , Wilkie , J , Zhao , Z Y & Tucker , J H R 2011 , ' Anthracene-modified oligonucleotides as fluorescent DNA mismatch sensors: discrimination between various base-pair mismatches ' SUPRAMOLECULAR CHEMISTRY , vol 23 , no. 3-4 , pp. 273-277 . DOI: 10.1080/10610278.2010.523117 |
Palavras-Chave | #/dk/atira/pure/subjectarea/asjc/1600 #Chemistry(all) |
Tipo |
article |