Tetra-end-linked oligonucleotides forming DNA G-quadruplexes: a new class of aptamers showing anti-HIV activity.

Autoria(s): Oliviero, G.; Amato, J.; Borbone, N.; D'Errico, S.; Galeone, A.; Mayol, L.; Haider, Shozeb; Olubiyi, O.; Hoorelbeke, B.; Balzarini, J.; Piccialli, G.
Data(s)

21/12/2010
Resumo

The biophysical and biological properties of unprecedented anti-HIV aptamers are presented. The most active aptamer (1L) shows a significant affinity to the HIV protein gp120.
Identificador

http://pure.qub.ac.uk/portal/en/publications/tetraendlinked-oligonucleotides-forming-dna-gquadruplexes-a-new-class-of-aptamers-showing-antihiv-activity(eb0f5ed6-40a7-4e89-bbd4-52f8d884f005).html

http://dx.doi.org/10.1039/c0cc02866e
Idioma(s)

eng
Direitos

info:eu-repo/semantics/restrictedAccess
Fonte

Oliviero , G , Amato , J , Borbone , N , D'Errico , S , Galeone , A , Mayol , L , Haider , S , Olubiyi , O , Hoorelbeke , B , Balzarini , J & Piccialli , G 2010 , ' Tetra-end-linked oligonucleotides forming DNA G-quadruplexes: a new class of aptamers showing anti-HIV activity. ' Chemical Communications , vol 46(47) , no. 47 , pp. 8971-8973 . DOI: 10.1039/c0cc02866e
Palavras-Chave #/dk/atira/pure/subjectarea/asjc/2500/2506 #Metals and Alloys #/dk/atira/pure/subjectarea/asjc/2500/2505 #Materials Chemistry #/dk/atira/pure/subjectarea/asjc/2500/2508 #Surfaces, Coatings and Films #/dk/atira/pure/subjectarea/asjc/2500/2504 #Electronic, Optical and Magnetic Materials #/dk/atira/pure/subjectarea/asjc/2500/2503 #Ceramics and Composites #/dk/atira/pure/subjectarea/asjc/1500/1503 #Catalysis #/dk/atira/pure/subjectarea/asjc/1600 #Chemistry(all)
Tipo

article
Acesso ao item digital