Detection of BRAF V600E mutation by pyrosequencing
| Data(s) |
01/03/2008
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| Resumo |
Introduction: Detection of the V600E hotspot mutation in BRAF oncogene is extremely useful for the screening of hereditary non-polyposis colorectal cancer (Lynch's syndrome) and for the prediction of sensitivity to MEK inhibitors. Here we describe a method for detecting this mutation based upon pyrosequencing technology. |
| Identificador | |
| Idioma(s) |
eng |
| Direitos |
info:eu-repo/semantics/restrictedAccess |
| Fonte |
Tan , Y H , Liu , Y Q , Eu , K W , Ang , P W , Li , W Q , Salto-Tellez , M , Iacopetta , B & Soong , R 2008 , ' Detection of BRAF V600E mutation by pyrosequencing ' Pathology , vol 40 , no. 3 , pp. 295-298 . DOI: 10.1080/00313020801911512 |
| Palavras-Chave | #/dk/atira/pure/subjectarea/asjc/2700/2734 #Pathology and Forensic Medicine |
| Tipo |
article |
