Positive association between nuclear Runx2 and oestrogen-progesterone receptor gene expression characterises a biological subtype of breast cancer


Autoria(s): Das, K.; Leong, D.T.; Gupta, A.; Shen, L.; Putti, T.; Stein, G.S.; Van Wijnen, A.J.; Salto-Tellez, Manuel
Data(s)

01/09/2009

Resumo

Purpose: The runt-related transcription factor, Runx2 may have an oncogenic role in mediating metastatic events in breast cancer, but whether Runx2 has a role in the early phases of breast cancer development is not clear. We examined the expression of Runx2 and its relationship with oestrogen receptor (ER) and progesterone receptor (PR) in breast cancer cell lines and tissues.

Identificador

http://pure.qub.ac.uk/portal/en/publications/positive-association-between-nuclear-runx2-and-oestrogenprogesterone-receptor-gene-expression-characterises-a-biological-subtype-of-breast-cancer(146dde1e-6527-4fa4-a04d-b74c0818a238).html

http://dx.doi.org/10.1016/j.ejca.2009.06.021

Idioma(s)

eng

Direitos

info:eu-repo/semantics/restrictedAccess

Fonte

Das , K , Leong , D T , Gupta , A , Shen , L , Putti , T , Stein , G S , Van Wijnen , A J & Salto-Tellez , M 2009 , ' Positive association between nuclear Runx2 and oestrogen-progesterone receptor gene expression characterises a biological subtype of breast cancer ' European Journal of Cancer , vol 45 , no. 13 , pp. 2239-2248 . DOI: 10.1016/j.ejca.2009.06.021

Palavras-Chave #/dk/atira/pure/subjectarea/asjc/1300/1306 #Cancer Research #/dk/atira/pure/subjectarea/asjc/2700/2730 #Oncology
Tipo

article