Novel linkage to chromosome 20p using latent classes of psychotic illness in 270 Irish high-density families


Autoria(s): Fanous, A.H.; Neale, M.C.; Webb, B.T.; Straub, R.E.; O'Neill, Francis; Walsh, D.; Riley, B.P.; Kendler, K.S.
Data(s)

15/07/2008

Resumo

Background: Several lines of evidence suggest that the clinical heterogeneity of schizophrenia is due to genetic heterogeneity. Genetic heterogeneity may decrease the signal-to-noise ratio in linkage and association studies. Therefore, linkage studies of clinically homogeneous classes of psychotic illness may result in greater power to detect at least some loci.

Identificador

http://pure.qub.ac.uk/portal/en/publications/novel-linkage-to-chromosome-20p-using-latent-classes-of-psychotic-illness-in-270-irish-highdensity-families(b1cd9eaf-30d0-4d4b-aedf-c97fc38a701c).html

http://dx.doi.org/10.1016/j.biopsych.2007.11.023

Idioma(s)

eng

Direitos

info:eu-repo/semantics/restrictedAccess

Fonte

Fanous , A H , Neale , M C , Webb , B T , Straub , R E , O'Neill , F , Walsh , D , Riley , B P & Kendler , K S 2008 , ' Novel linkage to chromosome 20p using latent classes of psychotic illness in 270 Irish high-density families ' Biological Psychiatry , vol 64 , no. 2 , pp. 121-127 . DOI: 10.1016/j.biopsych.2007.11.023

Palavras-Chave #/dk/atira/pure/subjectarea/asjc/2800/2803 #Biological Psychiatry
Tipo

article