Heat shock protein 70-mediated sensitization of cells to apoptosis by Carboxyl-Terminal Modulator Protein

Autoria(s): Piao, L.Z.; Li, Y.; Yang, K.J.; Park, K.A.; Byun, H.S.; Won, M.; Hong, J.; Kim, J.L.; Kweon, G.R.; Hur, G.M.; Seok, J.H.; Cho, J.Y.; Chun, T.; Hess, D.; Sack, R.; Maira, S.M.; Brazil, Derek; Hemmings, B.A.; Park, J.
Data(s)

15/07/2009
Resumo

Background: The serine/threonine protein kinase B (PKB/Akt) is involved in insulin signaling, cellular survival, and transformation. Carboxyl-terminal modulator protein (CTMP) has been identified as a novel PKB binding partner in a yeast two-hybrid screen, and appears to be a negative PKB regulator with tumor suppressor-like properties. In the present study we investigate novel mechanisms by which CTMP plays a role in apoptosis process.
Identificador

http://pure.qub.ac.uk/portal/en/publications/heat-shock-protein-70mediated-sensitization-of-cells-to-apoptosis-by-carboxylterminal-modulator-protein(0ce31e72-2995-4bc0-b4a2-4cc3bedae6b2).html

http://dx.doi.org/10.1186/1471-2121-10-53
Idioma(s)

eng
Direitos

info:eu-repo/semantics/restrictedAccess
Fonte

Piao , L Z , Li , Y , Yang , K J , Park , K A , Byun , H S , Won , M , Hong , J , Kim , J L , Kweon , G R , Hur , G M , Seok , J H , Cho , J Y , Chun , T , Hess , D , Sack , R , Maira , S M , Brazil , D , Hemmings , B A & Park , J 2009 , ' Heat shock protein 70-mediated sensitization of cells to apoptosis by Carboxyl-Terminal Modulator Protein ' BMC Cell Biology , vol 10 , 53 , pp. 53 . DOI: 10.1186/1471-2121-10-53
Palavras-Chave #/dk/atira/pure/subjectarea/asjc/1300/1307 #Cell Biology
Tipo

article
Acesso ao item digital