Endothelin receptor A blockade alters hemodynamic response to nitric oxide inhibition in rats.
| Data(s) |
1995
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| Resumo |
We examined the extent to which the systemic and renal vasoconstriction induced by nitric oxide (NO) inhibition in vivo is mediated by endothelin (ET). We examined the effects of BQ-610, a specific ETA-receptor antagonist, after NO inhibition with N omega-nitro-L-arginine methyl ester (L-NAME) in the anesthetized rat. Mean arterial pressure (MAP) increased after L-NAME infusion from 107 +/- 2 to 133 +/- 3 mmHg (P |
| Identificador | |
| Idioma(s) |
eng |
| Direitos |
info:eu-repo/semantics/restrictedAccess |
| Fonte |
Thompson , A , Valeri , C R & Lieberthal , W 1995 , ' Endothelin receptor A blockade alters hemodynamic response to nitric oxide inhibition in rats. ' The American journal of physiology , vol 269(2 Pt 2) , pp. H743-8 . |
| Tipo |
article |
