Folic acid use and major congenital malformations in offspring of women with epilepsy: a prospective study from the UK Epilepsy and Pregnancy Register


Autoria(s): Morrow, J.I.; Hunt, S.J.; Russell, A.J.; Smithson, W.H.; Parsons, L.; Robertson, I.; Waddell, R.; Irwin, B.; Morrison, Patrick; Craig, J.J.
Data(s)

01/05/2009

Resumo

Objective: In the general population, folic acid supplementation during pregnancy has been demonstrated to reduce the frequency of neural tube defects (NTDs) and other major congenital malformations (MCMs). It is recommended that women with epilepsy contemplating pregnancy take supplemental folic acid because of the known antifolate effect of some antiepileptic drugs (AEDs). Here the aim was to determine the effectiveness of this practice.

Identificador

http://pure.qub.ac.uk/portal/en/publications/folic-acid-use-and-major-congenital-malformations-in-offspring-of-women-with-epilepsy-a-prospective-study-from-the-uk-epilepsy-and-pregnancy-register(5f41e754-1da4-44b0-b1d4-25640e7c7a72).html

http://dx.doi.org/10.1136/jnnp.2008.156109

Idioma(s)

eng

Direitos

info:eu-repo/semantics/restrictedAccess

Fonte

Morrow , J I , Hunt , S J , Russell , A J , Smithson , W H , Parsons , L , Robertson , I , Waddell , R , Irwin , B , Morrison , P & Craig , J J 2009 , ' Folic acid use and major congenital malformations in offspring of women with epilepsy: a prospective study from the UK Epilepsy and Pregnancy Register ' JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY , vol 80 , no. 5 , pp. 506-511 . DOI: 10.1136/jnnp.2008.156109

Palavras-Chave #/dk/atira/pure/subjectarea/asjc/2700 #Medicine(all) #/dk/atira/pure/subjectarea/asjc/2700/2728 #Clinical Neurology #/dk/atira/pure/subjectarea/asjc/2700/2738 #Psychiatry and Mental health #/dk/atira/pure/subjectarea/asjc/2700/2746 #Surgery
Tipo

article