Prior colonisation with Candida species fails to guide empirical therapy for candidaemia in critically ill adults
Data(s) |
01/11/2010
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Resumo |
Objectives Pre-emptive fluconazole (fcz) anti-fungal therapy is often based upon Candida colonisation of at least 2 non-contiguous non-sterile sites. The aim of this study was to evaluate the relationship between candidaemia and prior colonisation of non-sterile sites. Methods A retrospective observational study was performed in the intensive care unit/high dependency unit (ICU/HDU) of a University hospital on alternate years from 1999–2007, where a pre-emptive anti-fungal therapy policy was introduced in 2005. Results A higher proportion of blood isolates were Candida glabrata compared with non-sterile isolates (16/46 vs 106/1062; p |
Formato |
application/pdf |
Identificador | |
Idioma(s) |
eng |
Direitos |
info:eu-repo/semantics/restrictedAccess |
Fonte |
Troughton , J A , Browne , G , McAuley , D , Walker , J M , Patterson , C & McMullan , R 2010 , ' Prior colonisation with Candida species fails to guide empirical therapy for candidaemia in critically ill adults ' Journal of Infection , vol 61 , no. 5 , pp. 403-409 . DOI: 10.1016/j.jinf.2010.08.013 |
Palavras-Chave | #/dk/atira/pure/subjectarea/asjc/2700/2726 #Microbiology (medical) #/dk/atira/pure/subjectarea/asjc/2700/2725 #Infectious Diseases |
Tipo |
article |