Fast, copper-free click chemistry: a convenient solid-phase approach to oligonucleotide conjugation
Data(s) |
2009
|
---|---|
Resumo |
Solid-phase oligonucleotide conjugation by nitrile oxide-alkyne click cycloaddition chemistry has been successfully demonstrated; the reaction, compatible with all nucleobases, requires no metal catalyst and proceeds under physiological conditions. |
Identificador | |
Idioma(s) |
eng |
Direitos |
info:eu-repo/semantics/restrictedAccess |
Fonte |
Singh , I , Vyle , J & Heaney , F 2009 , ' Fast, copper-free click chemistry: a convenient solid-phase approach to oligonucleotide conjugation ' Chemical Communications , vol 22 , no. 22 , pp. 3276-3278 . DOI: 10.1039/b904185k |
Palavras-Chave | #/dk/atira/pure/subjectarea/asjc/1500/1503 #Catalysis #/dk/atira/pure/subjectarea/asjc/1600 #Chemistry(all) #/dk/atira/pure/subjectarea/asjc/2500/2503 #Ceramics and Composites #/dk/atira/pure/subjectarea/asjc/2500/2504 #Electronic, Optical and Magnetic Materials #/dk/atira/pure/subjectarea/asjc/2500/2505 #Materials Chemistry #/dk/atira/pure/subjectarea/asjc/2500/2506 #Metals and Alloys #/dk/atira/pure/subjectarea/asjc/2500/2508 #Surfaces, Coatings and Films |
Tipo |
article |