Increased repair and cell survival in cells treated with DIR1 antisense oligonucleotides: implications for induced radioresistance


Autoria(s): Robson, Tracy; Price, M.E.; Moore, M.L.; Joiner, M.C.; McKelvey-Martin, V.J.; McKeown, S.R.; Hirst, David
Data(s)

2000

Resumo

Purpose: To determine whether repression of a recently isolated, X-ray-responsive gene, DIR1, using antisense oligonucleotides could affect clonogenic cell survival and repair of DNA strand breaks and have a possible role in the mechanism underlying the phenomenon of 'induced radioresistance' (IRR).

Identificador

http://pure.qub.ac.uk/portal/en/publications/increased-repair-and-cell-survival-in-cells-treated-with-dir1-antisense-oligonucleotides-implications-for-induced-radioresistance(ddb651df-abb1-4c16-b069-85ddbaa3d8b4).html

http://www.scopus.com/inward/record.url?scp=0034128724&partnerID=8YFLogxK

Idioma(s)

eng

Direitos

info:eu-repo/semantics/restrictedAccess

Fonte

Robson , T , Price , M E , Moore , M L , Joiner , M C , McKelvey-Martin , V J , McKeown , S R & Hirst , D 2000 , ' Increased repair and cell survival in cells treated with DIR1 antisense oligonucleotides: implications for induced radioresistance ' International journal of radiation biology , vol 76 , no. 5 , pp. 617-623 .

Palavras-Chave #/dk/atira/pure/subjectarea/asjc/1100/1101 #Agricultural and Biological Sciences (miscellaneous) #/dk/atira/pure/subjectarea/asjc/2700/2741 #Radiology Nuclear Medicine and imaging #/dk/atira/pure/subjectarea/asjc/3600/3614 #Radiological and Ultrasound Technology #/dk/atira/pure/subjectarea/asjc/2100/2104 #Nuclear Energy and Engineering #/dk/atira/pure/subjectarea/asjc/3100/3108 #Radiation
Tipo

article