Chemoenzymatic Synthesis of Carbasugars (+)-Pericosines A-C from Diverse Aromatic cis-Dihydrodiol Precursors


Autoria(s): Boyd, Derek; Sharma, Narain; Acaru, Carmen; Malone, John; O'Dowd, Colin; Allen, Christopher; Stevenson, Paul
Data(s)

21/05/2010

Resumo

cis-Dihydrocatechols, derived from biological cis-dihydroxylation of methyl benzoate, iodobenzene and benzonitrile, using the microorganism Pseudomonas putida UV4, were converted into pericosines A, C, and B, respectively. This approach constitutes the shortest syntheses, to date, of these important natural products with densely packed functionalities.

Identificador

http://pure.qub.ac.uk/portal/en/publications/chemoenzymatic-synthesis-of-carbasugars-pericosines-ac-from-diverse-aromatic-cisdihydrodiol-precursors(a3fff63f-4add-4592-9d2d-c2b4fc5b8cb8).html

http://dx.doi.org/10.1021/ol100525r

http://www.scopus.com/inward/record.url?scp=77952340928&partnerID=8YFLogxK

Idioma(s)

eng

Direitos

info:eu-repo/semantics/restrictedAccess

Fonte

Boyd , D , Sharma , N , Acaru , C , Malone , J , O'Dowd , C , Allen , C & Stevenson , P 2010 , ' Chemoenzymatic Synthesis of Carbasugars (+)-Pericosines A-C from Diverse Aromatic cis-Dihydrodiol Precursors ' Organic Letters , vol 12 , no. 10 , pp. 2206-2209 . DOI: 10.1021/ol100525r

Palavras-Chave #/dk/atira/pure/subjectarea/asjc/1300/1303 #Biochemistry #/dk/atira/pure/subjectarea/asjc/1600/1605 #Organic Chemistry #/dk/atira/pure/subjectarea/asjc/1600/1606 #Physical and Theoretical Chemistry
Tipo

article