Deletion of Irs2 causes reduced kidney size in mice: role for inhibition of GSK3 beta?
| Data(s) |
2010
|
|---|---|
| Resumo |
Background: Male Irs2(-/-) mice develop fatal type 2 diabetes at 13-14 weeks. Defects in neuronal proliferation, pituitary development and photoreceptor cell survival manifest in Irs2(-/-) mice. We identify retarded renal growth in male and female Irs2(-/-) mice, independent of diabetes. |
| Identificador |
http://dx.doi.org/10.1186/1471-213X-10-73 http://www.scopus.com/inward/record.url?scp=77954194860&partnerID=8YFLogxK |
| Idioma(s) |
eng |
| Direitos |
info:eu-repo/semantics/restrictedAccess |
| Fonte |
Carew , R M , Sadagurski , M , Goldschmeding , R , Martin , F , White , M F & Brazil , D 2010 , ' Deletion of Irs2 causes reduced kidney size in mice: role for inhibition of GSK3 beta? ' BMC Developmental Biology , vol 10 , 73 , pp. 73 . DOI: 10.1186/1471-213X-10-73 |
| Palavras-Chave | #/dk/atira/pure/subjectarea/asjc/1300/1309 #Developmental Biology |
| Tipo |
article |
