Transamidation reactions of  -lactams: a synthesis of ( )-dihydroperiphylline.


Autoria(s): Crombie, L.; Haigh, David; Jones, R.C.F.
Data(s)

1986

Resumo

Ammonolysis of N-(halogenoalkyl)azetidin-2-ones affords medium ring azalactams via transamidation but large or strained rings are not isolated, acyclic ?-amino-amides being produced; two successive transamidative ring expansions from 4-phenylazetidin-2-one give a synthesis of (?)-dihydroperiphylline (I).

Identificador

http://pure.qub.ac.uk/portal/en/publications/transamidation-reactions-of--lactams-a-synthesis-of--dihydroperiphylline(cd733d67-828c-4f27-8130-4dcdc7ba6489).html

Idioma(s)

eng

Direitos

info:eu-repo/semantics/restrictedAccess

Fonte

Crombie , L , Haigh , D & Jones , R C F 1986 , ' Transamidation reactions of  -lactams: a synthesis of ( )-dihydroperiphylline. ' Tetrahedron Letters , vol 27 , pp. 5151-5154 .

Tipo

article