The cost-effectiveness of the SPHERE intervention for the secondary prevention of coronary heart disease


Autoria(s): Gillespie, P.; O'Shea, E.; Murphy, A.W.; Byrne, M.C.; Byrne, M.; Smith, S.M.; Cupples, Margaret; Study Team, S.P.H.E.R.E.
Data(s)

01/07/2010

Resumo

Objectives: The Secondary Prevention of Heart disEase in geneRal practicE (SPHERE) trial has recently reported. This study examines the cost-effectiveness of the SPHERE intervention in both healthcare systems on the island of Ireland. Methods: Incremental cost-effectiveness analysis. A probabilistic model was developed to combine within-trial and beyond-trial impacts of treatment to estimate the lifetime costs and benefits of two secondary prevention strategies: Intervention - tailored practice and patient care plans; and Control - standardized usual care. Results: The intervention strategy resulted in mean cost savings per patient of 512.77 (95 percent confidence interval [CI], 1086.46-91.98) and an increase in mean quality-adjusted life-years (QALYs) per patient of 0.0051 (95 percent CI, 0.0101-0.0200), when compared with the control strategy. The probability of the intervention being cost-effective was 94 percent if decision makers are willing to pay €45,000 per additional QALY. Conclusions: Decision makers in both settings must determine whether the level of evidence presented is sufficient to justify the adoption of the SPHERE intervention in clinical practice. Copyright © Cambridge University Press 2010. <br/> <br/>

Formato

application/pdf

Identificador

http://pure.qub.ac.uk/portal/en/publications/the-costeffectiveness-of-the-sphere-intervention-for-the-secondary-prevention-of-coronary-heart-disease(80bdd947-2cb5-4f76-a4f4-e3d14bb1e664).html

http://dx.doi.org/10.1017/S0266462310000358

http://pure.qub.ac.uk/ws/files/673314/The%20cost-effectiveness%20of%20the%20SPHERE%20intervention%20for%20the%20secondary%20prevention%20of%20coronary%20heart%20disease%20-%20Int%20J%20Technol%20Assess%20Health%20Care%202010%20-%20Cupples%20ME.pdf

http://www.scopus.com/inward/record.url?scp=78049444223&partnerID=8YFLogxK

Idioma(s)

eng

Direitos

info:eu-repo/semantics/restrictedAccess

Fonte

Gillespie , P , O'Shea , E , Murphy , A W , Byrne , M C , Byrne , M , Smith , S M , Cupples , M & Study Team , S P H E R E 2010 , ' The cost-effectiveness of the SPHERE intervention for the secondary prevention of coronary heart disease ' International Journal of Technology Assessment in Health care , vol 26 , no. 3 , pp. 263-271 . DOI: 10.1017/S0266462310000358

Palavras-Chave #/dk/atira/pure/subjectarea/asjc/2700/2719 #Health Policy
Tipo

article