Expedient synthesis of (+)-trans-5-allylhexahydroindolizidin-3-one
| Data(s) |
08/04/2000
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|---|---|
| Resumo |
Treatment of the bicyclic iminium ion derived from 5-methoxyhexahydroindolizidin-3-one with allyltrimethylsilane gave exclusively the diastereoisomer in which the allyl group was axial. This substrate is a useful precursor to 5-propyl-3-alkylindolizidine alkaloids. (C) 1999 Elsevier Science Ltd. All rights reserved. |
| Identificador |
http://www.scopus.com/inward/record.url?scp=0034620228&partnerID=8YFLogxK |
| Idioma(s) |
eng |
| Direitos |
info:eu-repo/semantics/restrictedAccess |
| Fonte |
Potts , D , Stevenson , P & Thompson , N 2000 , ' Expedient synthesis of (+)-trans-5-allylhexahydroindolizidin-3-one ' Tetrahedron Letters , vol 41 , no. 2 , pp. 275-278 . |
| Palavras-Chave | #/dk/atira/pure/subjectarea/asjc/1300/1303 #Biochemistry #/dk/atira/pure/subjectarea/asjc/1600/1605 #Organic Chemistry #/dk/atira/pure/subjectarea/asjc/3000/3002 #Drug Discovery |
| Tipo |
article |
