Three component coupling reactions of N-acetyl-2-azetine-rapid stereoselective entry to 2,3,4-trisubstituted tetrahydroquinolines
| Data(s) |
07/03/2002
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|---|---|
| Resumo |
N-Acetyl-2-azetine undergoes Lewis acid catalysed [4 + 2]-cycloaddition with imines derived from aromatic amines and gave a 1:1 mixture of exo-endo diastereoisomeric azetidine cycloadducts which reacted further with aromatic amine, to give 2,3,4-trisubsitituted tetrahydroquinolines in good to excellent yield, predominantly as one diastereoisomer. |
| Identificador |
http://dx.doi.org/10.1039/b110242g http://www.scopus.com/inward/record.url?scp=0037034906&partnerID=8YFLogxK |
| Idioma(s) |
eng |
| Direitos |
info:eu-repo/semantics/restrictedAccess |
| Fonte |
Stevenson , P , Nieuwenhuyzen , M & Osborne , D 2002 , ' Three component coupling reactions of N-acetyl-2-azetine-rapid stereoselective entry to 2,3,4-trisubstituted tetrahydroquinolines ' Chemical Communications , vol 5 , no. 5 , pp. 444-445 . DOI: 10.1039/b110242g |
| Palavras-Chave | #/dk/atira/pure/subjectarea/asjc/1600 #Chemistry(all) |
| Tipo |
article |
