Soluble endostatin is a novel inhibitor of epithelial repair in idiopathic pulmonary fibrosis


Autoria(s): Richter, A.G.; McKeown, S.; Rathinam, S.; Harper, L.; Rajesh, P.; McAuley, Danny; Heljasvaara, R.; Thickett, D.R.
Data(s)

01/02/2009

Resumo

Background and aim: Aberrant angiogenesis and defective epithelial repair are key features of idiopathic pulmonary fibrosis (IPF). Endostatin is an antiangiogenic peptide with known effects on endothelial cells. This study aimed to establish the levels of endostatin in the bronchoalveolar lavage fluid (BALF) in IPF and to investigate its actions on distal lung epithelial cells (DLEC) and primary type II cells.

Identificador

http://pure.qub.ac.uk/portal/en/publications/soluble-endostatin-is-a-novel-inhibitor-of-epithelial-repair-in-idiopathic-pulmonary-fibrosis(025a7244-1a0c-42a7-84d0-d1e04a6473c2).html

http://dx.doi.org/10.1136/thx.2008.102814

http://www.scopus.com/inward/record.url?scp=60549105237&partnerID=8YFLogxK

Idioma(s)

eng

Direitos

info:eu-repo/semantics/restrictedAccess

Fonte

Richter , A G , McKeown , S , Rathinam , S , Harper , L , Rajesh , P , McAuley , D , Heljasvaara , R & Thickett , D R 2009 , ' Soluble endostatin is a novel inhibitor of epithelial repair in idiopathic pulmonary fibrosis ' Thorax , vol 64 , no. 2 , pp. 156-161 . DOI: 10.1136/thx.2008.102814

Palavras-Chave #/dk/atira/pure/subjectarea/asjc/2700/2740 #Pulmonary and Respiratory Medicine
Tipo

article