MMP expression and abnormal lung permeability are important determinants of outcome in IPF


Autoria(s): McKeown, S.; Richter, A.G.; O'Kane, Cecilia; McAuley, Danny; Thickett, D.R.
Data(s)

01/01/2009

Resumo

Matrix metalloproteinases (MMPs) degrade all of the extracellular matrix components of the intersititium and may play a role in abnormal alveolar permeability, which is a feature of idiopathic pulmonary fibrosis (IPF). The aims of the present study were to evaluate MMP protein levels in patients with IPF and determine any relationship to treatment and markers of permeability.

Identificador

http://pure.qub.ac.uk/portal/en/publications/mmp-expression-and-abnormal-lung-permeability-are-important-determinants-of-outcome-in-ipf(0af62ba6-196d-49b4-98ad-d767ce4110ba).html

http://dx.doi.org/10.1183/09031936.00060708

http://www.scopus.com/inward/record.url?scp=58849094483&partnerID=8YFLogxK

Idioma(s)

eng

Direitos

info:eu-repo/semantics/restrictedAccess

Fonte

McKeown , S , Richter , A G , O'Kane , C , McAuley , D & Thickett , D R 2009 , ' MMP expression and abnormal lung permeability are important determinants of outcome in IPF ' European Respiratory Journal , vol 33 , no. 1 , pp. 77-84 . DOI: 10.1183/09031936.00060708

Palavras-Chave #/dk/atira/pure/subjectarea/asjc/2700/2740 #Pulmonary and Respiratory Medicine
Tipo

article